DASB

DASB (4-Dimethylaminoethoxybenzaldehyde), is a compound used in scientific research. It is a selective radioligand for the serotonin transporter (SERT) and has been used in positron emission tomography (PET) studies to measure the density of SERT in the brain.

Chemistry

DASB belongs to the class of organic compounds known as benzaldehydes. These are organic aromatic compounds containing a benzene ring in which one hydrogen atom is replaced by an aldehyde group.

Uses

DASB is primarily used in scientific research, particularly in the field of neuroscience. It is a selective radioligand for the serotonin transporter (SERT), which means it binds specifically to this protein and can be detected using imaging techniques. This makes it a valuable tool for studying the role of serotonin in the brain and its involvement in various neurological and psychiatric disorders.

Research

Numerous studies have used DASB to investigate the density of SERT in the brain in conditions such as depression, anxiety disorders, and Parkinson's disease. These studies have provided valuable insights into the role of serotonin in these conditions and have potential implications for the development of new treatments.

See also

• Serotonin transporter
• Positron emission tomography
• Neuroscience

References

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