Dental lamina

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Dental Lamina

Diagram of dental lamina development

The dental lamina is a band of epithelial tissue seen in the development of the teeth. It is a critical structure in the embryonic development of the oral cavity, playing a key role in the formation of the primary dentition.

Development

The dental lamina begins to form during the sixth week of embryogenesis. It arises from the oral epithelium, which is a derivative of the ectoderm. The dental lamina is a horseshoe-shaped band that corresponds to the future dental arches.

As the embryo develops, the dental lamina invaginates into the underlying mesenchyme to form the tooth buds. These buds will eventually give rise to the enamel organ, which is responsible for the formation of enamel, the hard outer layer of the tooth.

Function

The primary function of the dental lamina is to initiate the formation of the teeth. It serves as the precursor to the tooth germ, which is the early structure that will develop into a tooth. The dental lamina also plays a role in the formation of the successional dental lamina, which gives rise to the permanent teeth.

Clinical Significance

Abnormalities in the development of the dental lamina can lead to various dental anomalies. For example, a failure in the formation of the dental lamina can result in anodontia, a condition characterized by the absence of teeth. Conversely, excessive activity of the dental lamina can lead to supernumerary teeth, which are extra teeth beyond the normal number.

Degeneration

After the primary teeth have formed, the dental lamina typically degenerates. However, remnants of the dental lamina can persist and may give rise to odontogenic cysts or tumors, such as the odontogenic keratocyst.

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Contributors: Prab R. Tumpati, MD