Dose profile
Dose Profile
A dose profile is a graphical representation of the distribution of radiation dose delivered across a particular plane or volume. It is a crucial concept in radiation therapy and medical imaging, where understanding the dose distribution is essential for both treatment planning and ensuring patient safety.
Overview
In the context of radiation therapy, a dose profile provides information about the intensity of radiation at different depths and lateral positions within the body. This information is used to optimize the delivery of therapeutic radiation to target tumors while minimizing exposure to surrounding healthy tissues.
Types of Dose Profiles
Dose profiles can be categorized based on the type of radiation used and the geometry of the beam:
- Photon Beam Profiles: These are used in external beam radiation therapy and are characterized by a central high-dose region with a gradual fall-off towards the edges. The image shown is an example of a dose profile for a 15 MV photon beam.
- Electron Beam Profiles: These profiles are typically more uniform across the beam width but have a rapid dose fall-off beyond a certain depth, known as the range of the electrons.
- Proton and Heavy Ion Beam Profiles: These profiles exhibit a distinct Bragg peak, where the dose is concentrated at a specific depth, allowing for precise targeting of deep-seated tumors.
Importance in Treatment Planning
Accurate dose profiles are essential for treatment planning systems (TPS) used in radiation therapy. They help in:
- Determining the isodose curves: These curves represent lines of equal dose and are used to visualize the dose distribution within the patient.
- Optimizing beam angles and intensities: By analyzing dose profiles, clinicians can adjust the angles and intensities of radiation beams to maximize tumor coverage and minimize exposure to healthy tissues.
- Quality assurance: Regular verification of dose profiles ensures that the radiation delivery system is functioning correctly and delivering the prescribed dose accurately.
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Contributors: Prab R. Tumpati, MD