Epidermolysis bullosa acquisita

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Epidermolysis bullosa acquisita (IPA: /ˌɛpɪdɜːrˈmoʊlɪsɪs bʊˈloʊsə ækˈwaɪzɪtə/) is a rare autoimmune skin condition that causes the skin to become fragile and form blisters in response to minor injury. The term is derived from the Greek words epidermis (the outer layer of skin), lysis (breakdown), bullosa (relating to blisters), and acquisita (acquired).

Symptoms

The primary symptom of epidermolysis bullosa acquisita is the formation of blisters on the skin following minor trauma. These blisters can occur anywhere on the body but are most common on the hands, feet, and face. Other symptoms can include itching, pain, and scarring.

Causes

Epidermolysis bullosa acquisita is caused by the body's immune system attacking a type of collagen found in the skin. This leads to the breakdown of the skin and the formation of blisters. The exact reason why this occurs is not fully understood.

Diagnosis

Diagnosis of epidermolysis bullosa acquisita is typically made through a combination of medical history, physical examination, and biopsy. A biopsy can confirm the presence of the disease by showing the characteristic changes in the skin.

Treatment

Treatment for epidermolysis bullosa acquisita primarily involves managing symptoms and preventing blisters from forming. This can include avoiding activities that can cause skin trauma, using protective bandages, and taking medications to suppress the immune system.

See also

External links

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