Estrogen deprivation therapy

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Estrogen Deprivation Therapy

Estrogen deprivation therapy (pronunciation: es-tro-gen de-pri-va-tion ther-a-py) is a form of hormone therapy used primarily in the treatment of breast cancer and other hormone-dependent cancers.

Etymology

The term "estrogen deprivation therapy" is derived from the hormone "estrogen," which is significant in the development and growth of some cancers, and "deprivation," which refers to the reduction or suppression of the hormone's presence in the body.

Overview

Estrogen deprivation therapy works by reducing the levels of estrogen in the body or by blocking its effects. This is achieved through the use of drugs such as aromatase inhibitors, which prevent the production of estrogen, or selective estrogen receptor modulators (SERMs), which block the effects of estrogen in the body.

Application

Estrogen deprivation therapy is often used in postmenopausal women with hormone receptor-positive breast cancer. It can also be used in premenopausal women, in combination with ovarian suppression therapy.

Related Terms

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