Extreme capsule
Extreme Capsule
The Extreme Capsule is a white matter tract in the brain that is involved in the communication between the insula and the prefrontal cortex. It is also known as the external capsule and is located between the claustrum and the insula.
Etymology
The term "Extreme Capsule" is derived from the Latin word "extremus" which means "outermost" and "capsula" which means "little box". This is in reference to its location in the brain, being the outermost capsule.
Anatomy
The Extreme Capsule is a white matter tract that is located between the insula and the claustrum. It is involved in the communication between the insula and the prefrontal cortex. The insula is a part of the cerebral cortex that is involved in consciousness, emotion, and the regulation of the body's homeostasis. The prefrontal cortex is involved in complex cognitive behavior, personality expression, decision making, and moderating social behavior.
Function
The Extreme Capsule plays a crucial role in the communication between the insula and the prefrontal cortex. This communication is important for the regulation of emotions, decision making, and social behavior. Disruptions in this communication can lead to a variety of neurological and psychiatric disorders.
Clinical Significance
Damage to the Extreme Capsule can result in a variety of neurological and psychiatric disorders. These can include aphasia, dementia, and schizophrenia. Aphasia is a condition that affects a person's ability to communicate, while dementia is a group of conditions characterized by impairment of at least two brain functions, such as memory loss and judgment. Schizophrenia is a long-term mental disorder involving a breakdown in the relation between thought, emotion, and behavior.
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Contributors: Prab R. Tumpati, MD