Factor V Leiden
Factor V Leiden
Factor V Leiden (pronounced: Factor Five Ley-den) is a mutation of one of the clotting factors in the blood known as factor V. This particular mutation can increase your chance of developing abnormal blood clots (thrombophilia), which can lead to conditions such as deep vein thrombosis or pulmonary embolism.
Etymology
The term "Factor V Leiden" is derived from the name of the city in the Netherlands where the mutation was first identified in 1994, Leiden. The "V" represents the Roman numeral for the number 5, indicating the fifth of the clotting factors.
Related Terms
- Thrombophilia: An abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels).
- Deep Vein Thrombosis (DVT): A blood clot that forms in a vein deep in the body, most often in the lower leg or the thigh.
- Pulmonary Embolism (PE): A condition that occurs when a blood vessel in the lungs gets blocked by a blood clot that has traveled from the leg or another part of the body.
- Mutation: A change in the DNA sequence of a gene.
- Clotting Factors: Proteins in the blood that work together to make blood clot.
See Also
External links
- Medical encyclopedia article on Factor V Leiden
- Wikipedia's article - Factor V Leiden
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