Formestane
Formestane
Formestane (/fɔːrˈmɛsteɪn/), also known as 4-hydroxyandrostenedione or 4-OHA, is a type of steroidal aromatase inhibitor used in the treatment of breast cancer. It is classified as a hormonal therapy and is primarily used in postmenopausal women.
Etymology
The term "Formestane" is derived from its chemical structure, which is formally known as 4-hydroxyandrost-4-ene-3,17-dione. The "-stane" suffix is common in the names of many steroids and related compounds.
Usage
Formestane works by inhibiting the aromatase enzyme, which is responsible for the conversion of androgens to estrogens in the body. By blocking this conversion, Formestane can help to reduce the levels of estrogen in the body, which can slow the growth of certain types of breast cancer cells that require estrogen to grow.
Related Terms
- Aromatase inhibitor: A class of drugs that block the production of estrogen in the body.
- Androgen: A type of hormone that plays a role in male traits and reproductive activity.
- Estrogen: A group of hormones that play an important role in the normal sexual and reproductive development in women.
- Breast cancer: A type of cancer that forms in the cells of the breasts.
See Also
External links
- Medical encyclopedia article on Formestane
- Wikipedia's article - Formestane
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