Functional neurologic disorder

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Functional neurologic disorder
Synonyms Conversion disorder, Functional neurological symptom disorder
Pronounce N/A
Specialty N/A
Symptoms Weakness, abnormal movement, non-epileptic seizures, sensory symptoms
Complications N/A
Onset Any age, commonly in adolescence or early adulthood
Duration Variable
Types N/A
Causes Psychological stress, trauma, neurological factors
Risks History of mental health disorders, stressful life events, family history
Diagnosis Clinical assessment, neurological examination, DSM-5 criteria
Differential diagnosis Epilepsy, multiple sclerosis, stroke, migraine
Prevention N/A
Treatment Cognitive behavioral therapy, physical therapy, medication
Medication N/A
Prognosis Variable, often chronic
Frequency Common, exact prevalence unknown
Deaths N/A


Functional Neurologic Disorder (FND) is a complex and multifaceted condition that affects the nervous system and how the brain and body communicate. It is characterized by neurological symptoms that are not explained by traditional neurological diseases or other medical conditions. FND encompasses a wide range of symptoms, including motor or movement disorders, sensory symptoms, and seizures that are not caused by epilepsy. These symptoms are genuine and can significantly impact an individual's quality of life, but they occur due to problems in the functioning of the nervous system rather than structural damage.

Etiology

The exact cause of FND is not fully understood, but it is believed to involve a combination of biological, psychological, and environmental factors. This multifactorial etiology suggests that FND lies at the intersection of neurology and psychiatry. Factors that may contribute to the development of FND include physical trauma, emotional stress, or a history of psychological conditions such as anxiety or depression. Additionally, some individuals may have a predisposition to developing FND due to genetic or other biological factors.

Symptoms

FND presents with a wide array of symptoms that can vary significantly from one person to another. Common symptoms include:

  • Motor Disorders: Such as weakness or paralysis, abnormal movements (tremors, dystonia, or myoclonus), and gait disorders.
  • Sensory Symptoms: Including numbness, tingling, or pain that does not follow typical neurological patterns.
  • Functional Seizures: Also known as non-epileptic seizures, these resemble epileptic seizures but are not associated with the abnormal electrical activity in the brain seen in epilepsy.
  • Cognitive Symptoms: Difficulties with concentration, memory, or speech.

Diagnosis

Diagnosing FND can be challenging, as symptoms often overlap with those of other neurological disorders. A comprehensive evaluation is necessary, including a detailed medical history, physical examination, and sometimes neuroimaging or other diagnostic tests to rule out other conditions. The diagnosis is primarily clinical and based on the presence of positive signs that are indicative of FND, as well as the absence of findings that would suggest an alternative diagnosis.

Treatment

Treatment of FND is tailored to the individual and often involves a multidisciplinary approach. Key components of treatment may include:

  • Physical Therapy: To improve movement disorders and manage physical symptoms.
  • Cognitive Behavioral Therapy (CBT): To address underlying psychological factors and help patients develop coping strategies.
  • Medication: While there is no specific medication for FND, medications may be used to manage associated conditions such as depression or anxiety.
  • Education: Educating patients and their families about FND is crucial for management and can help reduce stigma associated with the disorder.

Prognosis

The prognosis for individuals with FND varies. Some people may experience significant improvement with appropriate treatment, while others may have persistent symptoms. Early diagnosis and a comprehensive, multidisciplinary approach to treatment can improve outcomes.

See Also

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Contributors: Prab R. Tumpati, MD