GW-6471
GW-6471 is a chemical compound that acts as an antagonist of the peroxisome proliferator-activated receptor alpha (PPARα). It is primarily used in scientific research to study the role of PPARα in various physiological and pathological processes.
Chemical Structure and Properties
GW-6471 is a synthetic compound with the chemical formula C29H24N2O3. It is characterized by its ability to bind to the ligand-binding domain of PPARα, thereby inhibiting its activity. The compound is often used in laboratory settings to elucidate the function of PPARα in metabolic pathways.
Mechanism of Action
PPARα is a nuclear receptor that regulates the expression of genes involved in fatty acid metabolism, energy homeostasis, and inflammation. GW-6471 functions as an antagonist by binding to PPARα and preventing its activation by endogenous ligands. This inhibition allows researchers to study the effects of reduced PPARα activity in various biological contexts.
Applications in Research
GW-6471 is utilized in a variety of research applications, including:
- Metabolic Studies: By inhibiting PPARα, GW-6471 helps researchers understand the role of this receptor in lipid metabolism and energy balance.
- Cardiovascular Research: PPARα is implicated in the regulation of cardiovascular function, and GW-6471 is used to explore its potential as a therapeutic target in cardiovascular diseases.
- Inflammation and Immune Response: The compound is also used to investigate the involvement of PPARα in inflammatory processes and immune system regulation.
Safety and Handling
As with many research chemicals, GW-6471 should be handled with care. Appropriate safety measures, including the use of personal protective equipment and proper laboratory protocols, should be followed to minimize exposure and ensure safe handling.
Also see
- Peroxisome proliferator-activated receptor alpha
- Nuclear receptor
- Lipid metabolism
- Cardiovascular disease
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
