Gumma (pathology)

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Gumma
Synonyms
Pronounce	N/A
Specialty	N/A
Symptoms	Soft tumor, necrosis, granuloma
Complications	Tissue destruction, organ damage
Onset	Tertiary syphilis
Duration
Types	N/A
Causes	Treponema pallidum infection
Risks	Untreated syphilis
Diagnosis	Serology, biopsy
Differential diagnosis	Tuberculosis, sarcoidosis, leprosy
Prevention	Safe sex, syphilis treatment
Treatment	Antibiotics (penicillin)
Medication	Penicillin, doxycycline
Prognosis	Good with treatment
Frequency	Rare in developed countries
Deaths	N/A

Gummata hepatis

Wachsmoulage einer Gumma bei Siphilis

A gumma is a soft, non-cancerous growth resulting from the tertiary stage of syphilis, which is a sexually transmitted infection caused by the bacterium Treponema pallidum. Gummata can develop on any organ of the body, including the skin, bones, and internal organs, and can cause severe damage if left untreated.

Causes

Gumma is caused by the bacterium Treponema pallidum, which is responsible for syphilis. The bacterium is usually transmitted through sexual contact, but can also be passed from mother to child during pregnancy (congenital syphilis).

Symptoms

The symptoms of a gumma can vary depending on its location. If it develops on the skin, it may appear as a firm, painless lump that slowly erodes over time. If it develops on an internal organ, it can cause a variety of symptoms depending on the organ affected.

Diagnosis

Diagnosis of a gumma typically involves a physical examination and a review of the patient's medical history. Blood tests may also be performed to confirm the presence of Treponema pallidum.

Treatment

Treatment for a gumma typically involves antibiotics to kill the Treponema pallidum bacterium. In some cases, surgery may be required to remove the gumma.

See also

• Syphilis
• Treponema pallidum
• Congenital syphilis

References

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