Guthrie
Guthrie
Guthrie (pronounced: guh-th-ree) is a term with multiple meanings in the medical field. It is most commonly associated with the Guthrie test, a diagnostic tool used to screen newborns for certain metabolic disorders. The term is named after Dr. Robert Guthrie, who developed the test.
Etymology
The term Guthrie is derived from the surname of Dr. Robert Guthrie (1916-1995), an American microbiologist and physician. He developed the Guthrie test in the 1960s as a simple and inexpensive method to screen newborns for phenylketonuria (PKU), a metabolic disorder that can cause intellectual disability if not treated early.
Related Terms
- Guthrie test: A blood test used to screen newborns for certain metabolic disorders, including phenylketonuria (PKU) and congenital hypothyroidism. The test is performed by pricking the baby's heel and collecting a small sample of blood on a special filter paper.
- Phenylketonuria (PKU): A metabolic disorder that is screened for using the Guthrie test. Individuals with PKU are unable to break down the amino acid phenylalanine, which can build up in the blood and cause brain damage.
- Congenital hypothyroidism: Another disorder that is screened for using the Guthrie test. This condition occurs when a baby is born without a fully functioning thyroid, which can lead to growth and developmental problems.
- Newborn screening: The process of testing newborns for certain genetic, metabolic, and functional disorders. The Guthrie test is a key part of this process.
- Heel prick test: Another name for the Guthrie test, referring to the method of blood collection.
See Also
External links
- Medical encyclopedia article on Guthrie
- Wikipedia's article - Guthrie
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