Hibernoma
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Hibernoma | |
|---|---|
| |
| Synonyms | |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Usually asymptomatic, may present as a painless mass |
| Complications | Rarely, compression of adjacent structures |
| Onset | Typically in adults |
| Duration | Indefinite |
| Types | N/A |
| Causes | Unknown |
| Risks | |
| Diagnosis | Histopathology, Imaging studies |
| Differential diagnosis | Liposarcoma, Lipoma, Myxoid liposarcoma |
| Prevention | None |
| Treatment | Surgical excision |
| Medication | None |
| Prognosis | Excellent with complete excision |
| Frequency | Rare |
| Deaths | N/A |
Hibernoma is a rare, benign tumor that originates from brown fat tissue. The name "hibernoma" is derived from the tumor's resemblance to the brown fat found in hibernating animals.
History
The first known case of hibernoma was reported by Merkel in 1906. Since then, fewer than 200 cases have been reported in the medical literature.
Pathology
Hibernomas are composed of brown fat cells, which are larger than white fat cells and contain more mitochondria. These cells are responsible for heat production in the body, a process known as thermogenesis.
Clinical Presentation
Patients with hibernoma often present with a slow-growing, painless mass. The most common locations for hibernomas are the thigh, shoulder, back, and neck.
Diagnosis
The diagnosis of hibernoma is typically made through a combination of imaging studies and biopsy. On imaging, hibernomas appear as well-defined, vascular masses. The definitive diagnosis is made by biopsy, which shows the characteristic brown fat cells.
Treatment
The treatment for hibernoma is surgical removal. Because hibernomas are benign, they do not spread to other parts of the body, and complete removal is usually curative.
Prognosis
The prognosis for patients with hibernoma is excellent. After surgical removal, the recurrence rate is very low.
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Contributors: Prab R. Tumpati, MD
