Hollenhorst plaque
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| Hollenhorst plaque | |
|---|---|
| Synonyms | Retinal embolus |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Sudden vision loss, amaurosis fugax |
| Complications | Retinal artery occlusion, ischemic optic neuropathy |
| Onset | Sudden |
| Duration | Variable |
| Types | N/A |
| Causes | Cholesterol embolism |
| Risks | Atherosclerosis, carotid artery disease, cardiovascular disease |
| Diagnosis | Fundoscopy, fluorescein angiography |
| Differential diagnosis | Retinal vein occlusion, branch retinal artery occlusion |
| Prevention | Management of risk factors such as hypertension, hyperlipidemia |
| Treatment | Address underlying cause, antiplatelet therapy |
| Medication | N/A |
| Prognosis | Depends on extent of embolism and underlying conditions |
| Frequency | Rare |
| Deaths | N/A |
Hollenhorst plaque is a medical condition characterized by the presence of cholesterol crystals in the retinal arteries. These plaques are typically associated with a high risk of stroke and other cardiovascular diseases.
Introduction
Hollenhorst plaques are bright, refractile plaques that are usually seen in the retinal arterioles. They are named after Dr. Robert Hollenhorst, who first described them in 1961. These plaques are typically associated with a high risk of stroke and other cardiovascular diseases.
Causes
Hollenhorst plaques are caused by cholesterol crystals that have broken off from a larger plaque in the carotid artery. These crystals then travel through the bloodstream and become lodged in the smaller retinal arterioles.
Symptoms
The presence of a Hollenhorst plaque is often asymptomatic. However, if the plaque obstructs the blood flow to the retina, it can cause sudden, painless vision loss in one eye. This is known as amaurosis fugax.
Diagnosis
Hollenhorst plaques can be diagnosed through a comprehensive eye examination. This includes a dilated eye exam, where the doctor will look for the presence of plaques in the retinal arterioles.
Treatment
Treatment for Hollenhorst plaques typically involves managing the underlying cardiovascular disease. This can include medications to lower cholesterol levels, lifestyle changes such as diet and exercise, and in some cases, surgery to remove the plaque from the carotid artery.
Prognosis
The prognosis for individuals with Hollenhorst plaques is generally good, provided the underlying cardiovascular disease is managed effectively. However, these individuals are at a higher risk of stroke and other cardiovascular events.
See also
References
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Contributors: Prab R. Tumpati, MD