Homochlorcyclizine

Homochlorcyclizine.svg

Homochlorcyclizine is a first-generation antihistamine of the piperazine class. It is primarily used to treat allergic reactions, such as hay fever, urticaria, and allergic rhinitis. Homochlorcyclizine is known for its anticholinergic properties, which can lead to side effects such as dry mouth, drowsiness, and blurred vision.

Pharmacology

Homochlorcyclizine works by blocking the action of histamine at the H1 receptor sites. This action helps to alleviate the symptoms of allergic reactions. As a first-generation antihistamine, it can cross the blood-brain barrier, which is why it often causes sedation.

Uses

Homochlorcyclizine is used in the treatment of various allergic conditions, including:

• Allergic rhinitis
• Hay fever
• Urticaria
• Pruritus

Side Effects

Common side effects of homochlorcyclizine include:

• Drowsiness
• Dry mouth
• Blurred vision
• Constipation
• Urinary retention

Precautions

Patients should be cautious when using homochlorcyclizine if they have conditions such as:

• Glaucoma
• Prostatic hypertrophy
• Asthma
• Cardiovascular disease

Interactions

Homochlorcyclizine can interact with other medications, including:

• Alcohol
• Sedatives
• Tranquilizers
• Monoamine oxidase inhibitors (MAOIs)

See Also

• Antihistamine
• Allergic reaction
• Histamine
• H1 receptor

External Links

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