Homprenorphine
Homprenorphine is a semi-synthetic opioid that is derived from thebaine, a constituent of the opium poppy. It is used in the treatment of moderate to severe pain, and is also used in the treatment of opioid addiction. Homprenorphine is a partial agonist at the mu-opioid receptor, and an antagonist at the kappa-opioid receptor.
Pharmacology
Homprenorphine's pharmacological effects are due to its activity at the mu-opioid receptor, where it acts as a partial agonist. This means that while it can produce effects similar to those of full agonists such as morphine, its effects are limited by a ceiling effect. This can result in a lower risk of side effects such as respiratory depression.
At the kappa-opioid receptor, homprenorphine acts as an antagonist. This can result in a reduction in the dysphoric effects that can be associated with the use of other opioids.
Clinical Use
Homprenorphine is used in the treatment of moderate to severe pain. It can be used in both acute and chronic pain conditions. In addition to its use in pain management, homprenorphine is also used in the treatment of opioid addiction. It can help to reduce the symptoms of opioid withdrawal, and can also help to reduce the cravings for opioids that can occur in those with an addiction.
Side Effects
The side effects of homprenorphine can include nausea, vomiting, constipation, and drowsiness. It can also cause respiratory depression, although the risk of this is lower than with full opioid agonists. Other potential side effects can include itching, sweating, and dry mouth.
See Also
Transform your life with W8MD's budget GLP-1 injections from $125.
W8MD offers a medical weight loss program to lose weight in Philadelphia. Our physician-supervised medical weight loss provides:
- Most insurances accepted or discounted self-pay rates. We will obtain insurance prior authorizations if needed.
- Generic GLP1 weight loss injections from $125 for the starting dose.
- Also offer prescription weight loss medications including Phentermine, Qsymia, Diethylpropion, Contrave etc.
NYC weight loss doctor appointments
Start your NYC weight loss journey today at our NYC medical weight loss and Philadelphia medical weight loss clinics.
- Call 718-946-5500 to lose weight in NYC or for medical weight loss in Philadelphia 215-676-2334.
- Tags:NYC medical weight loss, Philadelphia lose weight Zepbound NYC, Budget GLP1 weight loss injections, Wegovy Philadelphia, Wegovy NYC, Philadelphia medical weight loss, Brookly weight loss and Wegovy NYC
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
