Ibotenic acid
Ibotenic Acid
Ibotenic Acid (/aɪˌboʊtɛˈnɪk ˈæsɪd/) is a naturally occurring neurotoxin produced by certain species of mushrooms, most notably the Amanita muscaria and Amanita pantherina species.
Etymology
The term "Ibotenic Acid" is derived from the Japanese word "ibotengu-take", which is a name for the mushroom Amanita muscaria. The suffix "-ic" is added to denote it as an acid.
Description
Ibotenic Acid is a powerful neurotoxin that acts as an agonist for certain neurotransmitter receptors, such as the N-Methyl-D-aspartate (NMDA) and trans-ACPD or metabotropic receptors in the brain and central nervous system. It is known to cause excitotoxicity by overstimulating these receptors.
Related Terms
- Neurotoxin: A type of poison that affects the nervous system.
- Agonist: A substance that initiates a physiological response when combined with a receptor.
- Neurotransmitter: A substance that transmits nerve impulses across a synapse.
- NMDA: A type of glutamate receptor in the brain.
- Excitotoxicity: Pathological process by which nerve cells are damaged and killed by excessive stimulation by neurotransmitters.
See Also
External links
- Medical encyclopedia article on Ibotenic acid
- Wikipedia's article - Ibotenic acid
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