Immunoglobulin g
Immunoglobulin G
Immunoglobulin G (IgG) is a type of antibody representing approximately 75% of serum antibodies in humans. IgG is the most common type of antibody found in blood circulation.
Pronunciation
Immunoglobulin G: /ɪˌmjuːnəʊˈɡlɒbjʊlɪn/ /dʒiː/
Etymology
The term "Immunoglobulin" is derived from the Latin "immunis" meaning exempt, and "globulin", which is a family of proteins. The "G" stands for "gamma", referring to the type of heavy chain found in this class of antibodies.
Function
Immunoglobulin G antibodies are involved in the secondary immune response, which is exposure to the same antigen for the second time. They are responsible for long-term immunity after vaccination or recovery from an infectious disease. IgG antibodies can cross the placenta, providing passive immunity to the fetus.
Types
There are four subclasses of IgG in humans, named IgG1, IgG2, IgG3, and IgG4. Each subclass varies in its biological features, function, and concentration in the blood.
Related Terms
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