Ipriflavone
Ipriflavone
Ipriflavone (pronounced: ip-ri-fla-vone) is a synthetic isoflavone which is used for the treatment and prevention of osteoporosis and other conditions related to bone loss.
Etymology
The term "Ipriflavone" is derived from its chemical structure, which is a modification of naturally occurring isoflavones. The prefix "Ipr-" is an acronym for the Italian pharmaceutical company that first synthesized it, Industria Prodotti Ricerca.
Usage
Ipriflavone is used to inhibit bone resorption, increase bone density and prevent osteoporosis in postmenopausal women. It is also used in the treatment of Paget's disease, a condition that affects the normal replacement of old bone tissue with new bone tissue.
Mechanism of Action
Ipriflavone acts by inhibiting the breakdown of bone (resorption) and stimulating the formation of new bone. It works by inhibiting the activity of osteoclasts, the cells that break down bone, and stimulating the activity of osteoblasts, the cells that build new bone.
Related Terms
- Isoflavone: A type of naturally occurring plant compound that has estrogen-like effects. Isoflavones are found in high amounts in soy products.
- Osteoporosis: A condition characterized by a decrease in the density of bone, decreasing its strength and resulting in fragile bones.
- Osteoclast: A type of bone cell that removes bone tissue by removing its mineralized matrix and breaking up the organic bone.
- Osteoblast: A type of cell that is responsible for forming new bone.
- Paget's disease: A chronic bone disorder that typically results in enlarged and deformed bones due to abnormal bone destruction and regrowth.
External links
- Medical encyclopedia article on Ipriflavone
- Wikipedia's article - Ipriflavone
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