Isocodeine
Isocodeine
Isocodeine (/ˌaɪsoʊˈkoʊdiːn/) is a semi-synthetic opioid analgesic and structural isomer of codeine. It was first synthesized in 1924 and is used as a pain reliever and cough suppressant.
Etymology
The term "Isocodeine" is derived from the prefix "iso-", from the Greek "ίσος" (isos), meaning "equal", and "codeine", a type of opioid. This refers to its structural similarity to codeine.
Pharmacology
Isocodeine is a prodrug that is metabolized in the liver by the cytochrome P450 enzyme system into its active form, morphine. It acts on the central nervous system (CNS) to provide pain relief and suppress coughing by decreasing the activity in the part of the brain that causes coughing.
Related Terms
- Opioid: A class of drugs that include the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone (OxyContin®), hydrocodone (Vicodin®), codeine, morphine, and many others.
- Codeine: A narcotic pain-reliever and cough suppressant similar to morphine and hydrocodone.
- Prodrug: A medication or compound that, after administration, is metabolized into a pharmacologically active drug.
- Morphine: A pain medication of the opiate family which is found naturally in a number of plants and animals.
See Also
External links
- Medical encyclopedia article on Isocodeine
- Wikipedia's article - Isocodeine
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