Isoform
Isoform
Isoform (pronounced: /ˈaɪsəʊfɔːm/) is a term used in molecular biology to refer to different versions of the same protein that are produced from the same gene through a process known as alternative splicing.
Etymology
The term "isoform" is derived from the Greek word "isos" meaning "equal", and the English word "form". This refers to the fact that isoforms are different forms of the same protein.
Definition
An isoform is a version of a protein that has the same function as the original protein but has a slightly different structure. This can occur as a result of alternative splicing, where different combinations of exons from the same gene are joined together to create different mRNA molecules, which are then translated into different protein isoforms.
Related Terms
- Alternative splicing: A process that can lead to the production of different protein isoforms from the same gene.
- Exon: A segment of a DNA or RNA molecule containing information coding for a protein or peptide sequence.
- Intron: A segment of a DNA or RNA molecule that does not code for proteins and interrupts the sequence of genes.
- mRNA: Messenger RNA, a type of RNA molecule that conveys genetic information from DNA to the ribosome, where they specify the amino acid sequence of the protein products of gene expression.
See Also
External links
- Medical encyclopedia article on Isoform
- Wikipedia's article - Isoform
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