Ivabradine hydrochloride
Ivabradine hydrochloride (pronunciation: eye-va-BRA-deen HYE-droe-KLOR-ide) is a medication used primarily in the treatment of certain types of heart disease and heart failure.
Etymology
The term "Ivabradine" is derived from its chemical structure, which is a derivative of benzazepinone. The suffix "-bradine" is used to denote its bradycardic effect, which means it slows the heart rate. The term "hydrochloride" refers to the hydrochloride salt form of the drug, which enhances its solubility and stability.
Pharmacology
Ivabradine hydrochloride works by selectively inhibiting the If current in the sinoatrial node, the natural pacemaker of the heart. This results in a reduction in heart rate, reducing the heart's workload and improving its efficiency.
Indications
Ivabradine hydrochloride is indicated for the treatment of stable angina pectoris (chest pain), chronic heart failure, and in certain cases, inappropriate sinus tachycardia. It is used when beta-blockers are contraindicated or not tolerated.
Side Effects
Common side effects of Ivabradine hydrochloride include bradycardia (slow heart rate), atrial fibrillation (irregular heart rhythm), luminous phenomena (visual disturbances), and nausea.
Related Terms
See Also
External links
- Medical encyclopedia article on Ivabradine hydrochloride
- Wikipedia's article - Ivabradine hydrochloride
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