Keratoderma climactericum

Keratoderma climactericum
Synonyms	Haxthausen's disease
Pronounce	N/A
Specialty	Dermatology
Symptoms	Thickening of the palms and soles
Complications	N/A
Onset	Menopause
Duration	Chronic
Types	N/A
Causes	Hormonal changes
Risks	Postmenopausal women
Diagnosis	Clinical examination
Differential diagnosis	Palmoplantar keratoderma, Psoriasis
Prevention	N/A
Treatment	Emollients, Keratolytics, Topical corticosteroids
Medication	N/A
Prognosis	N/A
Frequency	Rare
Deaths	N/A

Keratoderma climactericum is a rare, acquired, non-familial skin disorder that is characterized by the thickening of the skin on the palms of the hands and soles of the feet. It is most commonly seen in postmenopausal women and is often associated with hot flashes and sweating. The condition was first described by Haxthausen in 1901.

Symptoms and signs

The main symptom of keratoderma climactericum is the thickening of the skin on the palms and soles. This can lead to discomfort and pain, especially when walking or using the hands. Other symptoms can include redness, itching, and peeling of the skin. In some cases, the nails can also be affected, leading to nail dystrophy.

Causes

The exact cause of keratoderma climactericum is unknown. However, it is thought to be related to hormonal changes that occur during menopause. Some researchers believe that the condition may be triggered by a decrease in estrogen levels, which can affect the skin's ability to retain moisture.

Diagnosis

Diagnosis of keratoderma climactericum is usually based on the patient's symptoms and a physical examination of the skin. In some cases, a skin biopsy may be performed to confirm the diagnosis and rule out other conditions.

Treatment

Treatment for keratoderma climactericum typically involves the use of topical creams and ointments to help soften the skin and relieve symptoms. In severe cases, oral retinoids may be prescribed. In addition, patients are often advised to avoid activities that can exacerbate the condition, such as walking barefoot or using harsh soaps.

See also

• Keratoderma
• Menopause
• Skin disorder