Liquid chromatography–mass spectrometry

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Liquid chromatography–mass spectrometry
TermLiquid chromatography–mass spectrometry
Short definitionliquid chromatography–mass spectrometry (LIH-kwid KROH-muh-TAH-gruh-fee-mas-spek-TRAH-meh-tree) A laboratory technique that combines two different processes to measure the amount of different Separate, identify and measure substances in a liquid sample. In the liquid chromatography (LC) method, a liquid sample is passed through a column filled with a material that separates the different substances in the sample. 
TypeCancer terms
SpecialtyOncology
LanguageEnglish
SourceNCI
Comments


liquid chromatography–mass spectrometry - (pronounced) (LIH-kwid KROH-muh-TAH-gruh-fee-mas-spek-TRAH-meh-tree) A laboratory technique that combines two different processes to measure the amount of different Separate, identify and measure substances in a liquid sample. In the liquid chromatography (LC) method, a liquid sample is passed through a column filled with a material that separates the different substances in the sample. In the mass spectrometry (MS) part of the procedure, the separated substances then pass through a special machine that reports the molecular weight, structure, identity and number of the different substances in the sample. Liquid chromatography-mass spectrometry has many applications including screening for drugs, identifying toxins in the environment, and detecting certain metabolic disorders in infants. Also called LC-MS

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