List of bacterial vaginosis microbiota

From WikiMD's medical encyclopedia

Bacterial Vaginosis Microbiota is a complex and diverse community of microorganisms that inhabit the vaginal environment. This community plays a crucial role in maintaining vaginal health and preventing infections. However, when the balance of these microorganisms is disrupted, it can lead to a condition known as Bacterial Vaginosis (BV).

Overview

The vaginal microbiota is predominantly composed of Lactobacillus species, which are beneficial bacteria that help maintain the acidic pH of the vagina and prevent the growth of harmful bacteria. However, in women with BV, there is a significant decrease in Lactobacillus species and an overgrowth of anaerobic bacteria, leading to an increase in vaginal pH and the production of foul-smelling discharge.

List of Bacterial Vaginosis Microbiota

The following is a list of the most common bacteria found in the vaginal microbiota of women with BV:

  • Gardnerella vaginalis: This is the most common bacteria associated with BV. It adheres to the vaginal epithelial cells and forms a biofilm that protects other bacteria from the immune system and antibiotics.
  • Atopobium vaginae: This bacteria is often found in high numbers in women with BV and is associated with a more severe and recurrent form of the disease.
  • Mobiluncus species: These bacteria are curved rod-shaped and are often found in women with BV. They are associated with a higher risk of preterm birth and pelvic inflammatory disease.
  • Prevotella species: These bacteria are part of the normal vaginal microbiota but can overgrow in women with BV, leading to inflammation and increased risk of sexually transmitted infections.
  • Mycoplasma hominis: This bacteria is associated with BV and can cause inflammation and damage to the vaginal epithelial cells.

Treatment

The treatment of BV involves the use of antibiotics to reduce the overgrowth of harmful bacteria and restore the normal vaginal microbiota. The most commonly used antibiotics are Metronidazole and Clindamycin. Probiotics containing Lactobacillus species may also be used to help restore the normal vaginal microbiota.

See Also

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Contributors: Prab R. Tumpati, MD