Lycoperdonosis

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
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W8MD medical weight loss NYC and sleep center NYC

Lycoperdonosis
Puffball spores under scanning electron microscope
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Cough, dyspnea, fever, fatigue
Complications	Respiratory failure
Onset	Hours to days after exposure
Duration	Variable
Types	N/A
Causes	Inhalation of puffball spores
Risks	Exposure to puffball spores, especially in enclosed spaces
Diagnosis	Chest X-ray, CT scan, bronchoscopy, biopsy
Differential diagnosis	Hypersensitivity pneumonitis, pneumonia, asthma
Prevention	Avoid inhaling puffball spores
Treatment	Corticosteroids, supportive care
Medication	N/A
Prognosis	Generally good with treatment
Frequency	Rare
Deaths	N/A

Lycoperdon perlatum

Lycoperdonosis is a rare respiratory disease caused by the inhalation of large amounts of spores from mature puffballs, a type of fungus. It is a form of extrinsic allergic alveolitis, also known as hypersensitivity pneumonitis, an inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts.

Symptoms

The symptoms of lycoperdonosis are similar to those of other respiratory diseases and can include cough, fever, and difficulty breathing. In severe cases, it can lead to pulmonary fibrosis, a condition that causes the lungs to become scarred and can result in serious breathing problems.

Diagnosis

Diagnosis of lycoperdonosis can be challenging due to its rarity and the nonspecific nature of its symptoms. It is typically diagnosed based on a combination of clinical history, physical examination, and radiographic findings. Biopsy of the lung tissue may also be performed in some cases.

Treatment

Treatment for lycoperdonosis typically involves avoiding further exposure to puffball spores and treating the symptoms. In severe cases, corticosteroids may be used to reduce inflammation in the lungs. In cases where pulmonary fibrosis has developed, treatment options may be limited and can include lung transplantation.

Prevention

Prevention of lycoperdonosis primarily involves avoiding exposure to mature puffball spores. This can be achieved by not disturbing puffballs that are releasing spores and by wearing a mask when in areas where puffballs are present.

See also

• Hypersensitivity pneumonitis
• Pulmonary fibrosis
• Fungus

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