MOMS Trial
MOMS Trial
The MOMS Trial (Management of Myelomeningocele Study) is a significant medical research study that was conducted to evaluate the effectiveness and safety of prenatal surgery for myelomeningocele, the most severe form of spina bifida. The trial was sponsored by the National Institutes of Health (NIH) and was conducted from 2003 to 2010.
Pronunciation
The acronym MOMS is pronounced as /mɒmz/.
Etymology
The term "MOMS Trial" is an acronym derived from the phrase "Management of Myelomeningocele Study".
Overview
The MOMS Trial was a randomized controlled trial that compared the safety and efficacy of prenatal surgery with postnatal surgery for myelomeningocele. The trial involved multiple medical centers and was designed to determine whether prenatal surgery could reduce the need for shunting, improve motor outcomes, and improve the quality of life for children with myelomeningocele.
Results
The results of the MOMS Trial, published in 2011, showed that prenatal surgery for myelomeningocele reduced the need for shunting and improved motor outcomes at 30 months of age, but was associated with an increased risk of preterm delivery and uterine dehiscence at delivery.
Related Terms
- Myelomeningocele
- Spina Bifida
- Shunting
- National Institutes of Health
- Randomized Controlled Trial
- Prenatal Surgery
- Postnatal Surgery
- Uterine Dehiscence
External links
- Medical encyclopedia article on MOMS Trial
- Wikipedia's article - MOMS Trial
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