MYCBP

Ideogram human chromosome 1

== MYCBP ==

MYCBP, also known as MYC binding protein, is a protein that in humans is encoded by the MYCBP gene. It plays a crucial role in various cellular processes, particularly in the regulation of gene expression.

Structure

MYCBP is composed of multiple domains, including a MYC-binding domain that allows it to interact with the MYC oncoprotein. Additionally, it contains other functional domains that contribute to its role in transcriptional regulation.

Function

The primary function of MYCBP is to modulate the activity of the MYC protein, a transcription factor involved in cell proliferation and growth. By binding to MYC, MYCBP can influence the expression of genes that are important for cell cycle progression and tumorigenesis.

Clinical Significance

Aberrant expression or dysregulation of MYCBP has been associated with various diseases, including cancer. Studies have shown that alterations in MYCBP levels can impact cell growth and survival, highlighting its potential as a therapeutic target for cancer treatment.

Interactions

MYCBP interacts with a variety of proteins involved in different cellular pathways. These interactions play a crucial role in mediating the effects of MYCBP on gene expression and cellular processes.

See also

• MYC (gene)
• Gene expression
• Transcriptional regulation

References

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