Macrogol
Macrogol
Macrogol (pronunciation: /ˈmakrəˌgɔːl/), also known as polyethylene glycol (PEG), is a polyether compound widely used in a variety of pharmaceutical and industrial applications.
Etymology
The term "Macrogol" is derived from the Greek words "makros", meaning large, and "glykol", which refers to a sweet, syrupy substance. This name was given due to the compound's high molecular weight and its viscous nature.
Definition
Macrogol is a series of polymers that are derived from ethylene oxide. They are available in a wide range of molecular weights, from 300 to 10,000,000 Da. The number following "Macrogol" or "PEG" in the name of a compound indicates the average molecular weight of the polymer. For example, Macrogol 4000 has an average molecular weight of 4000 Da.
Uses
Macrogol is used in a variety of pharmaceutical applications. It is often used as a laxative to treat constipation, as it increases the amount of water in the intestinal tract to stimulate bowel movements. It is also used as a base for many topical creams and ointments, as it is non-irritating and does not absorb into the skin. In addition, it is used as a solvent, plasticizer, and humectant in various industrial applications.
Related Terms
External links
- Medical encyclopedia article on Macrogol
- Wikipedia's article - Macrogol
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