Mandibular lymph node

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Mandibular Lymph Node

Diagram of lymph nodes in the head and neck, including the mandibular lymph nodes.

The mandibular lymph node is a small, oval-shaped structure that is part of the lymphatic system. It is located near the lower jaw, or mandible, and plays a crucial role in the immune response by filtering lymphatic fluid and trapping pathogens.

Anatomy

The mandibular lymph nodes are situated along the lower border of the mandible. They are part of the superficial lymph nodes of the head and neck. These nodes receive lymph from the submental lymph nodes, buccal lymph nodes, and other surrounding tissues.

Location

The mandibular lymph nodes are typically found near the anterior border of the masseter muscle, close to the facial artery and vein. They are often palpable in cases of infection or inflammation in the areas they drain.

Structure

Each lymph node is encapsulated by a fibrous capsule and contains an outer cortex and an inner medulla. The cortex is rich in lymphocytes, which are crucial for the immune response. The medulla contains medullary cords and sinuses that facilitate the flow of lymph.

Function

The primary function of the mandibular lymph nodes is to filter lymphatic fluid from the tissues of the face and neck. They trap bacteria, viruses, and other foreign particles, preventing them from entering the bloodstream. The nodes also play a role in the activation of the immune system by presenting antigens to T cells and B cells.

Clinical Significance

Mandibular lymph nodes can become enlarged due to infections, such as tonsillitis, pharyngitis, or dental abscesses. Enlargement of these nodes is often a sign of localized infection or inflammation. In some cases, they may also be involved in systemic conditions such as lymphoma or metastatic cancer.

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Contributors: Prab R. Tumpati, MD