Meptazinol
Meptazinol
Meptazinol (/mɛpˈtæzɪnɒl/) is a opioid analgesic of the benzomorphan family. It is used in the treatment of moderate to severe pain, including pain in childbirth. It is believed to have a lower potential for addiction than other opioids.
Etymology
The name "Meptazinol" is derived from the chemical structure of the drug, which includes a methyl group (me-), a p-tolyl group (pt-), and an azinane ring (-azin-), with the suffix -ol indicating the presence of a hydroxyl group.
Pharmacology
Meptazinol works by binding to mu-opioid receptors in the brain and spinal cord, which are involved in the transmission of pain signals. It is a mixed agonist-antagonist opioid, meaning it both activates and blocks these receptors, which may contribute to its lower potential for addiction.
Related Terms
- Opioid: A class of drugs that includes natural, synthetic, and semi-synthetic substances, used primarily for their analgesic effects.
- Analgesic: A type of medication used to relieve pain.
- Benzomorphan: A family of opioids that includes drugs such as pentazocine and phenazocine.
- Mu-opioid receptor: A type of opioid receptor in the brain and spinal cord that is the primary target of most opioid drugs.
Side Effects
Common side effects of Meptazinol include nausea, vomiting, dizziness, and sweating. Less common side effects can include confusion, hallucinations, and changes in heart rate or blood pressure.
Contraindications
Meptazinol should not be used in patients with a history of hypersensitivity to the drug or other opioids. It should also be used with caution in patients with respiratory disease, liver or kidney disease, or a history of substance abuse.
External links
- Medical encyclopedia article on Meptazinol
- Wikipedia's article - Meptazinol
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