Merestinib
Merestinib
Merestinib (pronunciation: /mɛrɛstɪnɪb/) is a small molecule inhibitor used in the treatment of various types of cancer. It is an experimental drug that targets multiple kinases, including MET, AXL, and MERTK, which are often overexpressed or mutated in cancer cells.
Etymology
The name "Merestinib" is derived from the combination of the words "mere", which is Latin for "part" or "segment", and "stinib", a common suffix for kinase inhibitors. This reflects the drug's function as a part of a larger group of kinase inhibitors.
Mechanism of Action
Merestinib works by inhibiting the activity of certain kinases, which are enzymes that add a phosphate group to other proteins in a cell. By blocking these kinases, Merestinib can prevent cancer cells from growing and dividing, thereby slowing or stopping the progression of the disease.
Related Terms
- Kinase inhibitor: A type of drug that blocks the activity of kinases.
- MET: A gene that codes for a protein involved in cell growth and division. Mutations in this gene can lead to cancer.
- AXL: A gene that codes for a protein involved in cell survival and growth. Overexpression of this gene can contribute to cancer development.
- MERTK: A gene that codes for a protein involved in cell survival and growth. Mutations in this gene can lead to cancer.
See Also
External links
- Medical encyclopedia article on Merestinib
- Wikipedia's article - Merestinib
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