Metabolon
Metabolon
Metabolon (pronunciation: /mɛˈtæbəlɒn/) is a multi-protein complex that facilitates the sequential passage of substrate molecules through the active sites of different enzyme reactions. The term was first coined by Paul Srere in 1985.
Etymology
The term "metabolon" is derived from the Greek words "meta" meaning "after" and "bolē" meaning "a throw", which together imply a process of transformation or change.
Function
A metabolon is a temporary structural-functional complex formed by several enzymes and their substrates involved in sequential or related metabolic pathways. It allows for substrate channeling, a process that increases the rate and efficiency of metabolic pathways by passing intermediates directly from one enzyme to another.
Components
The metabolon complex is composed of multiple enzymes, substrates, and cofactors. The enzymes in a metabolon are often involved in the same metabolic pathway and work together to efficiently process substrates.
Related Terms
- Enzyme: A protein that acts as a biological catalyst to speed up a chemical reaction.
- Substrate: The molecule upon which an enzyme acts.
- Metabolic Pathway: A series of chemical reactions within a cell.
- Cofactor: A non-protein chemical compound or metallic ion that is required for an enzyme's activity.
See Also
External links
- Medical encyclopedia article on Metabolon
- Wikipedia's article - Metabolon
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