Methoxpropamine
Methoxpropamine (also known as MXP) is a dissociative anesthetic that is classified as a research chemical. It is a phenethylamine derivative with psychedelic and hallucinogenic effects.
History
Methoxpropamine was first synthesized in the 1940s as a potential analgesic and anesthetic. However, it was not until the 21st century that it gained popularity as a recreational drug.
Pharmacology
Methoxpropamine acts primarily as an NMDA receptor antagonist. By blocking the NMDA receptors, it prevents the action of glutamate, a neurotransmitter that is involved in memory, learning, and perception. This results in a disconnection between the conscious mind and the senses, leading to a state of dissociation.
Effects
The effects of methoxpropamine can vary greatly depending on the dose, the individual's physiology, and the method of administration. Common effects include feelings of euphoria, altered perception of time and space, visual and auditory hallucinations, and out-of-body experiences. At higher doses, it can cause confusion, dizziness, and loss of motor control.
Risks
Like other dissociative anesthetics, methoxpropamine carries a risk of physical and psychological dependence. It can also cause a range of negative side effects, including nausea, vomiting, increased heart rate, and respiratory depression. In severe cases, it can lead to unconsciousness or death.
Legal Status
The legal status of methoxpropamine varies by country. In some countries, it is classified as a controlled substance, while in others it is legal to possess for personal use.
See Also
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Contributors: Prab R. Tumpati, MD