Methylenedioxyphencyclidine

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Methylenedioxyphencyclidine

Chemical structure of Methylenedioxyphencyclidine

Methylenedioxyphencyclidine (MDPCP) is a synthetic dissociative drug that belongs to the arylcyclohexylamine class. It is chemically related to phencyclidine (PCP) and is known for its psychoactive effects, which include hallucinations, altered perceptions, and dissociation.

Chemical Structure

MDPCP is characterized by the presence of a methylenedioxy group attached to the phenyl ring of the phencyclidine structure. This modification is similar to that found in other psychoactive compounds such as 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxymethamphetamine (MDMA). The chemical structure of MDPCP can be represented as 1-(1-(3,4-methylenedioxyphenyl)cyclohexyl)piperidine.

Pharmacology

MDPCP acts primarily as an NMDA receptor antagonist, similar to PCP and ketamine. By blocking the NMDA receptor, MDPCP disrupts the normal functioning of the glutamate neurotransmitter system, leading to its dissociative effects. Users may experience a sense of detachment from their body and environment, as well as visual and auditory hallucinations.

Effects and Risks

The effects of MDPCP are dose-dependent and can vary significantly between individuals. Common effects include:

  • Dissociation and depersonalization
  • Euphoria
  • Altered sensory perceptions
  • Hallucinations

However, MDPCP also carries significant risks, including:

Legal Status

Due to its structural similarity to PCP and its potential for abuse, MDPCP is classified as a controlled substance in many countries. It is illegal to manufacture, possess, or distribute MDPCP without proper authorization.

Related Compounds

MDPCP is part of a broader class of dissociative anesthetics, which includes:

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Contributors: Prab R. Tumpati, MD