Metyrapone

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Metyrapone

Metyrapone (pronounced: meh-tye-RAH-pohn) is a drug used primarily in the diagnosis of adrenal insufficiency and occasionally in the treatment of Cushing's syndrome.

Etymology

The term "Metyrapone" is derived from its chemical name, 2-methyl-1,2-di(pyridin-3-yl)propan-1-one.

Usage

Metyrapone is an inhibitor of the enzyme 11β-hydroxylase, which plays a crucial role in the production of cortisol in the adrenal gland. By inhibiting this enzyme, Metyrapone reduces the production of cortisol, allowing physicians to assess the functionality of the patient's adrenal glands.

Related Terms

  • Adrenal Insufficiency: A condition in which the adrenal glands do not produce enough cortisol. Metyrapone is used in the diagnosis of this condition.
  • Cushing's Syndrome: A condition caused by an excess of cortisol in the body. Metyrapone may be used in the treatment of this condition.
  • 11β-Hydroxylase: An enzyme involved in the production of cortisol. Metyrapone inhibits this enzyme.
  • Cortisol: A hormone produced in the adrenal gland. Metyrapone reduces the production of this hormone.

External links

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