Microsatellite Instability
| Microsatellite Instability | |
|---|---|
| Term | Microsatellite Instability |
| Short definition | Microsatellite Instability - (pronounced) (MY-kroh-SA-teh-lite in-stuh-BIH-lih-tee) change that occurs in certain cells (such as cancer cells) in which the number of repeating DNA bases in a microsatellite (a short, repeating sequence of DNA) is different than the inheritance of the microsatellite. Microsatellite instability can be caused by errors that are not corrected when DNA is copied into a cell. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
Microsatellite Instability - (pronounced) (MY-kroh-SA-teh-lite in-stuh-BIH-lih-tee) change that occurs in certain cells (such as cancer cells) in which the number of repeating DNA bases in a microsatellite (a short, repeating sequence of DNA) is different than the inheritance of the microsatellite. Microsatellite instability can be caused by errors that are not corrected when DNA is copied into a cell. It is most commonly found in colon cancer, stomach cancer, and endometrial cancer, but can also be found in many other cancers. Knowing if a cancer has microsatellite instability can help plan the best treatment. Also called MSI
External links
- Medical encyclopedia article on Microsatellite Instability
- Wikipedia's article - Microsatellite Instability
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