Monckeberg's arteriosclerosis

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Monckeberg's arteriosclerosis (pronunciation: monk-eh-berg's ar-teer-ee-oh-skleh-roh-sis) is a form of arteriosclerosis, a broad term for the thickening and hardening of the arteries.

Etymology

The condition is named after Johann Georg Monckeberg, a German pathologist who first described the condition in 1903.

Definition

Monckeberg's arteriosclerosis, also known as Monckeberg's medial calcific sclerosis or Monckeberg's sclerosis, is characterized by calcification of the media, the middle layer of the arterial wall. Unlike other forms of arteriosclerosis, such as atherosclerosis, it does not involve the intima, the innermost layer of the arterial wall, and therefore does not cause significant narrowing of the arterial lumen.

Symptoms and Diagnosis

Monckeberg's arteriosclerosis is often asymptomatic and is usually discovered incidentally during radiographic imaging or surgery. When symptoms do occur, they are typically related to the affected organ system. For example, if the arteries supplying the legs are affected, symptoms may include claudication or ischemia. Diagnosis is typically confirmed through imaging studies such as X-ray, CT scan, or ultrasound, which can reveal the characteristic calcifications in the arterial wall.

Treatment

There is currently no specific treatment for Monckeberg's arteriosclerosis. Management typically involves addressing any underlying conditions that may contribute to vascular calcification, such as diabetes mellitus or chronic kidney disease, and implementing lifestyle modifications to improve overall vascular health.

Related Terms

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