Multiple System Atrophy
Multiple System Atrophy
Multiple System Atrophy (pronunciation: /ˈmʌltɪpəl ˈsɪstəm ˈætrəfi/) is a rare, progressive neurodegenerative disorder characterized by a combination of symptoms that affect both the autonomic nervous system (the part of the nervous system that controls involuntary action such as blood pressure or digestion) and movement.
The term "Multiple System Atrophy" (MSA) was first introduced in 1969 by Graham and Oppenheimer who grouped together several similar disorders under this name. The etymology of the term comes from the Latin multus (many), systema (an organized whole), and atrophia (wasting away), reflecting the multiple systems in the body that are affected by this disease.
Symptoms
The symptoms of MSA vary and can include ataxia (problems with coordination and balance), parkinsonism (slowness, rigidity, tremor and problems with balance), and dysautonomia (problems with autonomic functions including changes in blood pressure, bowel and bladder function, and difficulties with sexual function).
Diagnosis
Diagnosis of MSA is challenging due to its varied symptoms. It is often initially misdiagnosed as Parkinson's disease, but as it progresses, the additional symptoms can lead to the correct diagnosis.
Treatment
There is currently no cure for MSA, but there are treatments available to help manage symptoms. These can include medications to manage low blood pressure, physical therapy to help with movement problems, and other supportive treatments.
Prognosis
The prognosis for individuals with MSA varies but the condition is progressive and currently incurable. The average lifespan after diagnosis is 6 to 9 years, but this can vary widely.
See Also
External links
- Medical encyclopedia article on Multiple System Atrophy
- Wikipedia's article - Multiple System Atrophy
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