NTHL1 gene
| NTHL1 gene | |
|---|---|
| Term | NTHL1 gene |
| Short definition | NSAID - (pronounced) A drug that works differently than a steroid to reduce pain, redness, swelling, and fever in the body. Some NSAIDs can also help prevent blood clots from forming. |
| Type | Cancer terms |
| Specialty | Oncology |
| Language | English |
| Source | NCI |
| Comments | |
NTHL1 gene - A gene that makes a protein involved in repairing DNA damage. Mutations (changes) in the NTHL1 gene can prevent cells from repairing their damaged DNA, which can lead to the growth of cancerous cells. The mutated NTHL1 gene has been found in some patients with an inherited condition called familial adenomatous polyposis 3 (FAP3). FAP3 causes many polyps (abnormal growths) to form on the inner walls of the colon and rectum, which can lead to colon cancer. People with NTHL1 mutations may also be at increased risk of developing other types of cancer, including endometrial, small bowel, skin, breast, and pancreatic cancer
External links
- Medical encyclopedia article on NTHL1 gene
- Wikipedia's article - NTHL1 gene
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