Nitromifene
Nitromifene
Nitromifene (pronounced: /ˈnaɪtroʊmɪˌfiːn/) is a nonsteroidal selective estrogen receptor modulator (SERM) that was never marketed. It is a derivative of triphenylethylene and is related to other triphenylethylene SERMs such as clomifene and tamoxifen.
Etymology
The term "Nitromifene" is derived from its chemical structure, which includes a nitro group (NO2) and is similar to that of clomifene and tamoxifen, hence the suffix "-mifene".
Pharmacology
As a SERM, Nitromifene acts as an antagonist of the estrogen receptor in some tissues such as the breast and acts as an agonist in other tissues such as the bone and uterus. This selective action allows it to block the growth-promoting effects of estrogen in some tissues, which can be beneficial in the treatment of diseases such as breast cancer.
Related Terms
External links
- Medical encyclopedia article on Nitromifene
- Wikipedia's article - Nitromifene
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