Novavax COVID-19 vaccine
== Novavax COVID-19 Vaccine ==
The Novavax COVID-19 vaccine, also known as NVX-CoV2373, is a protein subunit vaccine developed by Novavax for the prevention of COVID-19. The vaccine is designed to stimulate an immune response against the SARS-CoV-2 virus, which causes COVID-19.
Development and Approval
The development of the Novavax COVID-19 vaccine began in early 2020. The vaccine uses a recombinant nanoparticle technology to generate an immune response. It includes a Matrix-M adjuvant to enhance the body's immune response to the vaccine.
In clinical trials, the Novavax vaccine demonstrated high efficacy in preventing symptomatic COVID-19 infection. It has been authorized for emergency use in several countries and is under review by various health authorities worldwide.
Mechanism of Action
The Novavax COVID-19 vaccine works by introducing a protein subunit of the SARS-CoV-2 virus into the body. This protein is harmless on its own but is recognized by the immune system as a foreign invader. The immune system then produces antibodies and trains T cells to recognize and fight the actual virus if the person is exposed in the future.
Administration
The vaccine is administered as an intramuscular injection, typically in two doses given several weeks apart. The exact schedule may vary based on regulatory guidelines and ongoing research.
Efficacy and Safety
Clinical trials have shown that the Novavax COVID-19 vaccine is highly effective in preventing COVID-19, including severe disease and hospitalization. Common side effects include pain at the injection site, fatigue, headache, and muscle pain. These side effects are generally mild and resolve within a few days.
Storage and Distribution
The Novavax vaccine can be stored at standard refrigerator temperatures, making it easier to distribute compared to some other COVID-19 vaccines that require ultra-cold storage.
Related Pages
See Also
- Pfizer–BioNTech COVID-19 vaccine
- Moderna COVID-19 vaccine
- Johnson & Johnson COVID-19 vaccine
- AstraZeneca COVID-19 vaccine
References
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Contributors: Prab R. Tumpati, MD