Obligate carrier
Obligate Carrier
Obligate Carrier (pronunciation: /ˈɒblɪɡət ˈkærɪər/) is a term used in genetics to describe an individual who is a carrier of a recessive gene that leads to a genetic disorder and passes the gene to their offspring.
Etymology
The term "obligate carrier" is derived from the Latin word "obligatus", meaning bound or compelled, and the English word "carrier". In the context of genetics, it refers to an individual who is bound by their genetic makeup to carry and potentially pass on a specific genetic trait or disorder.
Definition
An obligate carrier is an individual who carries one copy of a mutated gene associated with a recessive disorder. This individual does not exhibit symptoms of the disorder, as they also carry a normal copy of the gene. However, they are "obligated" to pass on the mutated gene to their offspring. If both parents are obligate carriers for the same disorder, there is a 25% chance that their child will inherit the disorder.
Related Terms
- Genetic Disorder: A disease caused by abnormalities in an individual's genetic material.
- Recessive Gene: A gene that is masked by a dominant gene and does not express itself unless it is paired with another recessive gene.
- Carrier: An individual who carries and can pass on a genetic trait or mutation but does not exhibit symptoms of the associated disorder.
- Mutation: A change in the DNA sequence that makes up a gene.
See Also
External links
- Medical encyclopedia article on Obligate carrier
- Wikipedia's article - Obligate carrier
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