Obliterating endarteritis

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Obliterating endarteritis
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Synonyms Endarteritis obliterans
Pronounce N/A
Specialty N/A
Symptoms Claudication, pain, ulceration
Complications Gangrene, tissue necrosis
Onset Variable, often gradual
Duration Chronic
Types N/A
Causes Atherosclerosis, autoimmune disorders, smoking
Risks Smoking, diabetes, hypertension
Diagnosis Angiography, Doppler ultrasound
Differential diagnosis Peripheral artery disease, Buerger's disease
Prevention Smoking cessation, control of diabetes, exercise
Treatment Medications, surgery, lifestyle changes
Medication N/A
Prognosis Variable, depends on severity and treatment
Frequency Common in smokers and individuals with diabetes
Deaths N/A


Obliterating endarteritis is a pathological condition characterized by the inflammation and subsequent occlusion of the inner layer of an artery. This condition is often associated with various diseases such as syphilis, tuberculosis, and rheumatoid arthritis.

Causes

The primary cause of obliterating endarteritis is the inflammation of the inner layer of an artery. This inflammation can be triggered by various factors, including:

  • Infection: Certain infections, particularly syphilis and tuberculosis, can lead to obliterating endarteritis.
  • Autoimmune diseases: Conditions such as rheumatoid arthritis can also cause this condition.
  • Vascular diseases: Diseases that affect the blood vessels, such as atherosclerosis, can also lead to obliterating endarteritis.

Symptoms

The symptoms of obliterating endarteritis can vary depending on the affected artery. However, common symptoms include:

  • Pain in the affected area
  • Reduced blood flow to the affected area
  • Swelling and inflammation

Diagnosis

Diagnosis of obliterating endarteritis typically involves a combination of physical examination, medical history, and imaging tests. These may include:

  • Angiography: This imaging test uses X-rays and a special dye to visualize the blood vessels.
  • Ultrasound: This test uses sound waves to create images of the blood vessels.
  • MRI: This imaging test uses a magnetic field and radio waves to create detailed images of the blood vessels.

Treatment

Treatment for obliterating endarteritis typically involves managing the underlying cause of the condition. This may include:

  • Antibiotics: If the condition is caused by an infection, antibiotics may be prescribed.
  • Anti-inflammatory drugs: These drugs can help reduce inflammation and pain.
  • Surgery: In severe cases, surgery may be required to remove the affected portion of the artery.

See also

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Contributors: Prab R. Tumpati, MD