Omadacycline

Omadacycline

Omadacycline (pronounced oh-ma-da-cy-cline) is a tetracycline class antibiotic used for the treatment of various bacterial infections. It is a broad-spectrum antibiotic that is effective against both Gram-positive and Gram-negative bacteria.

Etymology

The term "Omadacycline" is derived from the parent class of antibiotics it belongs to, the tetracyclines, with the prefix "Oma-" possibly referring to its unique chemical structure or its developer, the pharmaceutical company Paratek Pharmaceuticals.

Usage

Omadacycline is used to treat community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI). It is administered either orally or intravenously.

Mechanism of Action

Omadacycline inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit of the bacteria, preventing the addition of new amino acids to the growing peptide chain.

Side Effects

Common side effects of Omadacycline include nausea, vomiting, and diarrhea. Less common but more serious side effects can include allergic reactions, photosensitivity, and potential harm to the fetus in pregnant women.

Related Terms

• Tetracycline
• Antibiotic
• Gram-positive bacteria
• Gram-negative bacteria
• Community-acquired bacterial pneumonia
• Acute bacterial skin and skin structure infections
• Protein synthesis
• Nausea
• Vomiting
• Diarrhea
• Allergic reactions
• Photosensitivity
• Fetus

External links

• Medical encyclopedia article on Omadacycline
• Wikipedia's article - Omadacycline

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