Ormeloxifene
Ormeloxifene (pronunciation: /ɔːrmɛˈlɒksɪfiːn/), also known as Centchroman, is a selective estrogen receptor modulator (SERM) that is used in the form of an oral contraceptive in India. It is marketed under the trade names Saheli, Novex, and Novex-DS, among others.
Etymology
The name "Ormeloxifene" is derived from the chemical structure of the drug, which is an oxime derivative of a compound related to the synthetic estrogen Chlormadinone acetate.
Pharmacology
Ormeloxifene is a non-hormonal contraceptive with a unique mechanism of action. It acts as an anti-estrogen in the uterus and breast, but as an estrogen in the bone, heart, and brain. This selective action makes it a valuable drug in the treatment of various gynecological disorders.
Medical Uses
Ormeloxifene is primarily used as a contraceptive but is also found effective in the treatment of dysfunctional uterine bleeding and menorrhagia. It is also being studied for its potential use in the treatment of breast cancer.
Side Effects
The most common side effects of Ormeloxifene include nausea, weight gain, and delayed menses. Less common side effects include headache, dizziness, and breast discomfort.
Related Terms
- Selective estrogen receptor modulator
- Contraceptive
- Dysfunctional uterine bleeding
- Menorrhagia
- Breast cancer
See Also
External links
- Medical encyclopedia article on Ormeloxifene
- Wikipedia's article - Ormeloxifene
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