Orobol
Orobol is a naturally occurring isoflavone, a type of phytoestrogen, found in various plants. It is a metabolite of the isoflavone biochanin A, and has been found to have various biological activities, including antioxidant, anti-inflammatory, and anticancer properties.
Chemical Structure and Properties
Orobol has a chemical formula of C16H12O4 and a molecular weight of 268.26 g/mol. It is a member of the isoflavones, a subclass of the flavonoid family of compounds. The structure of orobol consists of a chromone backbone, with two phenolic hydroxyl groups attached at the 7 and 4' positions.
Sources
Orobol is found in a variety of plants, including the red clover (Trifolium pratense), the kudzu vine (Pueraria lobata), and the soybean (Glycine max). It is also a metabolite of the isoflavone biochanin A, which is found in high concentrations in red clover.
Biological Activities
Orobol has been found to have a number of biological activities. It has been shown to have antioxidant properties, helping to neutralize harmful free radicals in the body. It also has anti-inflammatory effects, and has been found to inhibit the production of pro-inflammatory cytokines.
In addition, orobol has been found to have anticancer properties. It has been shown to inhibit the growth of various types of cancer cells, including breast, prostate, and colon cancer cells. It does this by inducing apoptosis, or programmed cell death, in the cancer cells.
Potential Therapeutic Uses
Due to its biological activities, orobol has potential therapeutic uses in the treatment of various conditions. Its antioxidant and anti-inflammatory properties may make it useful in the treatment of conditions such as rheumatoid arthritis and atherosclerosis. Its anticancer properties may make it a potential treatment for various types of cancer.
However, more research is needed to fully understand the potential therapeutic uses of orobol.
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