Oxyphil cell (pathology)
Oxyphil cell (pathology)
Oxyphil cells (pronunciation: /ˈɒksɪfɪl/), also known as oxyntic cells, are a type of cell found in the parathyroid gland and thyroid gland. The term "oxyphil" is derived from the Greek words "oxys" meaning sharp or acid, and "philos" meaning loving, referring to the cell's affinity for acidic dyes.
Function
Oxyphil cells are believed to be involved in the production and secretion of parathyroid hormone (PTH), which plays a crucial role in maintaining calcium homeostasis in the body. However, the exact function of these cells is not fully understood.
Histology
Histologically, oxyphil cells are larger than the more common chief cells of the parathyroid gland. They have a granular, eosinophilic cytoplasm due to the presence of numerous mitochondria.
Pathology
In pathology, the presence of oxyphil cells can be indicative of certain diseases. For example, an increase in the number of oxyphil cells is often seen in hyperparathyroidism, a condition characterized by an overproduction of PTH.
See also
References
External links
- Medical encyclopedia article on Oxyphil cell (pathology)
- Wikipedia's article - Oxyphil cell (pathology)
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