Pemphigoid nodularis
Pemphigoid Nodularis
Pemphigoid nodularis (pronunciation: pem-fig-oid no-dew-lar-is) is a rare variant of Bullous Pemphigoid, a chronic autoimmune skin disorder.
Etymology
The term 'Pemphigoid' is derived from the Greek word 'pemphix', meaning 'blister'. 'Nodularis' is a Latin term, referring to the nodular or lump-like appearance of the skin lesions in this condition.
Definition
Pemphigoid nodularis is characterized by the presence of pruritic, or itchy, nodules and blisters on the skin. It is a form of Bullous Pemphigoid, which is a more common condition characterized by large, fluid-filled blisters.
Symptoms
The primary symptom of Pemphigoid nodularis is the presence of itchy, nodular skin lesions. These may be accompanied by blisters, similar to those seen in Bullous Pemphigoid. The nodules are typically hard and may be painful.
Causes
Pemphigoid nodularis is an autoimmune disorder, which means it is caused by the body's immune system attacking its own tissues. The exact cause of this immune response is not known, but it is thought to be triggered by certain medications or underlying health conditions.
Diagnosis
Diagnosis of Pemphigoid nodularis is typically made through a combination of clinical examination, patient history, and skin biopsy. The biopsy can confirm the presence of the characteristic blisters and nodules, and can also help to rule out other potential causes of the symptoms.
Treatment
Treatment for Pemphigoid nodularis typically involves managing the symptoms and preventing complications. This may include the use of topical or oral corticosteroids to reduce inflammation and itching, as well as other medications to suppress the immune system and prevent further damage to the skin.
Related Terms
External links
- Medical encyclopedia article on Pemphigoid nodularis
- Wikipedia's article - Pemphigoid nodularis
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