Perifollicular mucinosis
Perifollicular Mucinosis
Perifollicular Mucinosis (pronunciation: per-i-fo-lik-yuh-lar myoo-si-noh-sis) is a rare dermatological condition characterized by the accumulation of mucin around the hair follicles.
Etymology
The term "Perifollicular Mucinosis" is derived from three Latin words: "Peri" meaning around, "Folliculus" meaning small bag (referring to hair follicle), and "Mucinosis" referring to the accumulation of mucin.
Definition
Perifollicular Mucinosis is a histopathological term used to describe the presence of excessive mucin around the hair follicles. Mucin is a complex glycoprotein that is secreted by the epithelial cells and is a major component of the mucus that protects and lubricates many tissues in the body.
Symptoms
The primary symptom of Perifollicular Mucinosis is the appearance of small, flesh-colored or pinkish bumps around the hair follicles. These bumps may be localized or widespread and are often accompanied by mild itching.
Causes
The exact cause of Perifollicular Mucinosis is unknown. However, it is often associated with other skin conditions such as Lupus Erythematosus and Alopecia Areata. It is also seen in patients with mycosis fungoides, a type of cutaneous T-cell lymphoma.
Diagnosis
Diagnosis of Perifollicular Mucinosis is primarily based on the clinical presentation and histopathological examination of the skin lesions. The presence of excessive mucin around the hair follicles, as seen under a microscope, confirms the diagnosis.
Treatment
Treatment of Perifollicular Mucinosis is aimed at managing the symptoms and treating any underlying conditions. Topical corticosteroids and retinoids may be used to reduce inflammation and itching. In severe cases, systemic therapies such as methotrexate or cyclosporine may be considered.
Related Terms
- Mucin
- Hair Follicle
- Dermatology
- Histopathology
- Lupus Erythematosus
- Alopecia Areata
- Mycosis Fungoides
External links
- Medical encyclopedia article on Perifollicular mucinosis
- Wikipedia's article - Perifollicular mucinosis
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